Soluble M6P/IGF2R Released by TACE Controls Angiogenesis via Blocking Plasminogen Activation
نویسندگان
چکیده
منابع مشابه
Soluble M6P/IGF2R released by TACE controls angiogenesis via blocking plasminogen activation.
RATIONALE The urokinase plasminogen activator (uPA) system is among the most crucial pericellular proteolytic systems associated with the processes of angiogenesis. We previously identified an important regulator of the uPA system in the mannose 6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R). OBJECTIVE Here, we wanted to clarify whether and how did the soluble form of M6P/IGF2R...
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ژورنال
عنوان ژورنال: Circulation Research
سال: 2011
ISSN: 0009-7330,1524-4571
DOI: 10.1161/circresaha.110.234732